To The Editor: 

I read your editorial on “Will MO Go to Pot?” (and) I would like to offer you some credible information you should consider for future articles. “Why Marijuana Will Not Fix the Opioid Epidemic” is an article from Missouri Medicine Newsletter May/June 2018 from a physician’s viewpoint, with references. The second is a brief report that appeared in the September 2017 issue of Discover magazine about the high environmental consequences of growing pot. These consequences increase when states like Colorado, Washington, California relax current marijuana laws.

Please view “Chronic,” a documentary produced by the state of Idaho (vimeo.com/280127474). The video does a very good job of documenting the impact in states that first changed the law accepting artisanal (crude) marijuana.

The other resource I would encourage you to view is the documentation compiled by Rocky Mountain HIDTA (High Intensive Drug Trafficking Area). HIDTA centers are a federal program compiling intelligence for law enforcement by federal officers, state agencies and local departments. Their latest report on Colorado is at www.rmhidta.org. Click on the REPORT tab and the latest report is Vol 5.

Those making decisions concerning marijuana should understand the recent science and products are significantly different than the marijuana prior to 1992. That is the year the first such endogenous compound was isolated, just two years after the cloning of the CB1 receptor. This was the endogenous cannabinoid (endocannabinoid) anandamide. Now science knows the neurotransmitter and the location of the CB1 and CB2 receptors in the brain. Most all research used marijuana under 10 percent THC with relative few over 10 percent, and none with the high level extracts that can be as high as 99 percent THC.  

Combine this new product with a new delivery method, vaping. This is why those seeking legalization are in such a hurry to get laws passed. They have expressed concern if the new science and understanding of the new product becomes known by the general public they will be unable to get any pro-marijuana law passed. 

There is no accepted medical use of artisanal (crude) by credible medical entity. Marijuana is an unstable compound making every dose different. We don’t have unstable medicines. In addition we are no longer dealing with the common sativa or indica plant, but hundreds of variants. Which plant, at what time postharvest, would be the optimum dose, strength, variant and ratio cannabinoid (over 100) for what illness? No one in the world can or will be able to answer that question in the best interest of the patient.

I am a retired law enforcement officer who worked undercover for the Missouri State Highway Patrol. I have studied the drug and specifically the marijuana impact since the 1970s. 

Ed Moses 

Warrenton 

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